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CapitalBio Corporation capitalbiotm dna microarray
Overall sensitivity of the <t> DNA microarray </t> for the M. tuberculosis strains identification
Capitalbiotm Dna Microarray, supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Overall sensitivity of the DNA microarray for the M. tuberculosis strains identification

Journal: BMC Infectious Diseases

Article Title: Rapid and accurate detection of RMP- and INH- resistant Mycobacterium tuberculosis in spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study

doi: 10.1186/1471-2334-12-303

Figure Lengend Snippet: Overall sensitivity of the DNA microarray for the M. tuberculosis strains identification

Article Snippet: Among them, the CapitalBio™ DNA microarray that incorporate specific nucleotides at a given position of the rpoB , inhA and katG gene has been developed by CapitalBio Corporation to detect tuberculosis and its multi-drug resistant form in M. tuberculosis isolates and sputum specimens with notable sensitivity and specificity [ , , ].

Techniques: Microarray

Hybridization pattern of spinal tuberculosis specimens with the DNA microarray. a . Hybridization pattern of the M. tuberculosis strain identification (white frame) b . RMP resistance with the rpoB 531 (T C G->T T G) mutation, the hybridization signal of probe TCG531TTG (solid rectangle) being higher than corresponding wild-type probe (dashed rectangle) c . RMP resistance test: rpoB 516 (G A C->G T C) mutation, the hybridization signal of probe GAC516GTC (solid rectangle) being higher than corresponding wild-type probe (dashed rectangle) d , e . INH resistance test: katG 315 (A G C->A C C) mutation, the hybridisation signal of probe katG AGC315ACC (solid rectangles) were higher than corresponding wild-type probe (dashed rectangles) e. INH resistance test: inhA -15 C-T mutation, the hybridisation signal of probe inhA 15C→T (solid rectangles) were higher than corresponding wild-type probe (dashed rectangles).

Journal: BMC Infectious Diseases

Article Title: Rapid and accurate detection of RMP- and INH- resistant Mycobacterium tuberculosis in spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study

doi: 10.1186/1471-2334-12-303

Figure Lengend Snippet: Hybridization pattern of spinal tuberculosis specimens with the DNA microarray. a . Hybridization pattern of the M. tuberculosis strain identification (white frame) b . RMP resistance with the rpoB 531 (T C G->T T G) mutation, the hybridization signal of probe TCG531TTG (solid rectangle) being higher than corresponding wild-type probe (dashed rectangle) c . RMP resistance test: rpoB 516 (G A C->G T C) mutation, the hybridization signal of probe GAC516GTC (solid rectangle) being higher than corresponding wild-type probe (dashed rectangle) d , e . INH resistance test: katG 315 (A G C->A C C) mutation, the hybridisation signal of probe katG AGC315ACC (solid rectangles) were higher than corresponding wild-type probe (dashed rectangles) e. INH resistance test: inhA -15 C-T mutation, the hybridisation signal of probe inhA 15C→T (solid rectangles) were higher than corresponding wild-type probe (dashed rectangles).

Article Snippet: Among them, the CapitalBio™ DNA microarray that incorporate specific nucleotides at a given position of the rpoB , inhA and katG gene has been developed by CapitalBio Corporation to detect tuberculosis and its multi-drug resistant form in M. tuberculosis isolates and sputum specimens with notable sensitivity and specificity [ , , ].

Techniques: Hybridization, Microarray, Mutagenesis

Performance of the DNA microarray assay for detection of resistance to INH and RMP compared with phenotypic DST

Journal: BMC Infectious Diseases

Article Title: Rapid and accurate detection of RMP- and INH- resistant Mycobacterium tuberculosis in spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study

doi: 10.1186/1471-2334-12-303

Figure Lengend Snippet: Performance of the DNA microarray assay for detection of resistance to INH and RMP compared with phenotypic DST

Article Snippet: Among them, the CapitalBio™ DNA microarray that incorporate specific nucleotides at a given position of the rpoB , inhA and katG gene has been developed by CapitalBio Corporation to detect tuberculosis and its multi-drug resistant form in M. tuberculosis isolates and sputum specimens with notable sensitivity and specificity [ , , ].

Techniques: Microarray